Abstract
Graft-versus-Host Disease ( GVHD ) is a well-know complication of allogeneic bone marrow transplantation and is increasingly being recognized after solid-organ transplantation and transfusion.The radiation dose currently accepted to prevent GVHD is typically 15 Gy to 50 Gy. Blood irradiators are now in widespread use in the blood irradiation rather than LINACs because their security and convenient. Therefore, evaluated the dosimetry of blood irradiator is very important to confirm the safty of patients. Many research workers have investigated the glow curve and dynamic of CVD diamond film fabricated with chemical vapour deposition methods ( CVD method ). This work is to study CVD diamond as a tool for blood irradiator dosimetry. We were measured the absorption dose distribution and spacial dose distribution of sample container of blood irradiator (Gamma- cell). Results of experiment show that the response of absolute dose was display linearity(R-square 0.9853)for CVD diamond in high dose region ( 5-30 Gy),and measurement uncertainty is about 5%. The average absorbed dose is about 27.9± 5.46 Gy and the center absorbed dose is about 26 Gy of sample container of the blood-irradiator.The CVD diamond is a practical material for blood-irradiator measurements.