Abstract
Because of their widespread occurrence in a large variety of natural products, for example, drechslerines A and B bicycle[3.2.1]octanones remain a focus of attention for synthetic organic chemists. Recently, we have found that the bicyclo[2.2.2]octenone derivatives, which can be obtained from the Diels-Alder reaction of masked-o-benzoquinone with various dienophiles, upon direct irradiation in acetone furnished the ODPM (oxa-di-π-methane) rearrangement product. Herein we propose a route to bicycle[3.2.1]octanone derivatives via opening the three-member ring of tricyclo[3.3.0.02,8]octan-3-one.