Abstract
To manipulate mammalian cells precisely in micron size scale is getting important and concerned during the development aspect of biomedical engineering. In this study, magnetic force microscope was applied to measure the magnetization state of the track structures, and select the most suitable aspect ratio of the ellipse track magnetic film arrays. Magnetic thin films were manufactured using micro-fabrication technology as the track of carrier transportation. The movements of the magnetic carriers following the track could be controlled under the manipulation of rotating external magnetic fields. The carriers could be loaded by living cells containing magnetic beads, and manipulated to specific sites according to the external and additional magnitude fields. We have designed ellipse and cylindrical microcarriers which are applied to operational experiments, including the straight line, the back-forth, the change track, and other kinds of movements. In this study, a new magnetic carriers to manipulated the movements of living cells was manufactured and proved the functions. It would be utilized to detection in medicine and biology in the future.