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綠色螢光蛋白與綠豆脂質運輸蛋白基因之結合表現於原生質體之分析
Thesis

綠色螢光蛋白與綠豆脂質運輸蛋白基因之結合表現於原生質體之分析

張楓瀅
Masters, 國立清華大學, 生物資訊與結構生物研究所
2004

Abstract

脂質運輸蛋白 綠色螢光蛋白 原生質體 PEG轉殖法
The original objectives of this research were to examine the distribution of lipid transfer protein (LTP) and monitor the transport pathway of LTP in plants by means of fusion to enhanced green fluorescence protein (EGFP). This research was done using the mungbean VrLtp1 cDNA fused to EGFP. Plasmids p35S□-VrspLTP1-EGFP-NOS, p35S□-EGFP-NOS, p35S□-NOS and p35S□-Vrsp1-EGFP-NOS were constructed and transiently expressed in protoplasts prepared from tobacco mesophyll and soybean suspension cells. The transient expression was detected by fluorescence microscopy and measured using a multilabel counter fluorometer. The green light emission by the protoplasts transformed with p35S□-EGFP-NOS was detected under a fluorescent microscope. Interestingly, protoplasts transformed with p35S□-VrspLTP1-EGFP-NOS exhibited bright yellowish green fluorescence with deformed shape. Using the Multilabel Counter Victor3 to measure EGFP expression, the EGFP counts in protoplasts transformed with p35S□-VrspLTP1-EGFP-NOS and p35S□-EGFP-NOS were similar, about 3.2 and 3.4 fold of that of the control. Our results indicate that the p35S□-VrspLTP1-EGFP-NOS fusion protein was expressed in protoplasts and the fusion protein can be used for further study on localization of lipid transfer protein.

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