Abstract
Abstract The poly(amidoamine) dendrimer is a new type polymer which discovered by D. A. Tomalia et al. in 1984. The dendrimer has attracted scientist’s attention for the recent years. It possesses some important advantages, like monodispersity, porosity, high aqueous resolution, low viscosity, variety of structure design, and has a number of potential applications for medical science, biotechnology and optics science yet. The key points of investigation are to study the chemical change of dendrimer under thermal condition to obtain the surface energy change；we use Thermal Desorption-Atmospheric Pressure Ionization Mass-spectroscopy to support reason. The poly(amidoamine) dendrimer self-assembling on a silicon wafer between nano-gap gold electrodes，then gold nanoparticles is established on the surface between electrodes.This method provide us a simple、fast and cheaper way.