Abstract
In this thesis, a novel transverse magneto-optical Kerr effect (TMOKE) on the composite surface plasmon grating is proposed and developed to implement a label-free, high-sensitive optical biosensor. The Au/Fe/Au grating structure is designed and optimized to achieve maximal Kerr parameter. The device area is 25x14 mm2 and is integrated with a single microfludic channel for delivering liquid for test. After fabricating the device, we characterize the magneto-optical effect of the Au/Fe/Au plasmon grating and capabilities of detecting bio-molecules. The measured maximum of Kerr parameter is about 0.035 and a very dispersive near the SPP wavelength. Through this integrated magneto-optics device, we have demonstrated detection of NaCl in salt solution in low concentrations. The calculated detection of limit is around 10-7 RIU, corresponding to a minimal concentration of 0.004% (wt). Moreover, we investigate avidin/bBSA binding and show a result of real-time monitoring of avidin and bBSA interaction. The minimum detectable concentration of avidin is measured to be around 1.5nM. Our device could be fabricated by a nanoimprinting technique for mass production and integrated with microfludic channels for implementing a lab-on-chip system to detect bio-molecules.