Abstract
Abstract Active grab sampling is the most conventional method for monitoring pollutants in the aquatic environment. However, for those contaminants whose concentrations vary tremendously over time such as ultra-trace and bio-accumulated substances, it is inevitable to increase the frequency and time of sampling to reach the detectable concentration for further online instrumental detection. The use of passive samplers compensates those problems, which is suitable for consecutively sampling for a long lasting period. Polar organic chemical integrative sampler (POCIS) employed in the sampling, and followed by the evaluation of the medicine dosage from the community waste water can improve the insufficiency of recent technologies and information in nowadays. This research focuses on the dosage of drugs in aqueous environment. The POCIS manufactured by ourselves was employed in simulative experiments as well as in the field sampling. POCIS was exposed for 1, 3, 5, 7, 9, 15, 18 days in 14 different analytes at a concentration of 500 ppt, followed by the solid-phaseextraction from the adsorbent for pretreatment and HPLC-MS/MS for detection. The results of this simulation experiments have shown that POCIS could collect the analytes efficiently. The sampling concentration increased with sampling periods which could be used for establishing simulation curves and further estimating the concentration of water source. The results from active grab sampling and POCIS are highly correlated as expected. The difference between two methods could arise from the different sampling environments, and the most serious one is the effect on the rate of water flow. POCIS does not require electricity and intensive labor cost as well as the pretreatment method which is consistent with the environment-friendly purpose of green chemistry.