Abstract
The thesis describes Pd(0) catalyzed termolecular queuing processes involving allenes(RCH=C=CH2), aryl iodides(Ar-I), diboron((OR’)2B-B(OR’)2) and aldehydes(R’’-CHO). The reaction is believed to proceed via a three component coupling of allenes, aryl iodides and diboron to give allylic boronates in which the aryl group adding to the middle carbon and the boryl grup adding to the unsubstituted terminal carbon of the allene, followed by allylation of aldedydes to furnish the resulting homoallylic alcohols in fair to excellent yields. The catalytic reaction is highly regio- and stereoselective. This synthetic method tolerates a wide variety of functional groups present in the aryl iodides. A plausible mechanism is proposed to account for this palladium catalyzed reaction.