Abstract
The poly(amidoamine) dendrimer is a new type polymer which discovered by D. A. Tomalia et al. in 1984. The dendrimer has attracted scientist’s attention for the past decades. It possesses some important advantages, like monodispersity, porosity, high aqueous resolution, low viscosity, variety of structure design, and has a number of potential applications for medical science, biotechnology and optics science yet. The key points of investigation are to study the chemical change of dendrimer under various conditions. The physical and chemical properties are investigated for the different heating temperature, immersing in the different concentration of acid and basic solution, as well as in the various kinds of organic solvent. Since the morphology of dendrimer self-assembling on the silicon wafer can not be directly observed by electronic microscopy or by current instrument, the developed method of research is to indirectly observe the density changes by way of gold nanoparticle binding with amine functional groups on the substrate under the kinds of conditions, different heating temperature, immersing in the different concentration of acid and basic solution. The study can as also used ad the basis of developing lab-on-chip (LOC).