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A convenient and highly stereoselective approach for α-galactosylation performed by galactopyranosyl dibenzyl phosphite with remote participating groups
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A convenient and highly stereoselective approach for α-galactosylation performed by galactopyranosyl dibenzyl phosphite with remote participating groups

Yu-Pei Cheng, Hui-Ting ChenChun-Cheng Lin
Tetrahedron Letters, 卷.43(43), 頁碼.7721-7723
10/2002

摘要

Biochemistry Drug Discovery Organic Chemistry
By using 4- and 6-acyl remote group participation, a galactosyl phosphite donor exhibits exceptionally high α-anomeric selectivity for primary and secondary hydroxyl acceptors. It was observed that temperature played an important factor in glycosylation. The higher α-selectivities were obtained at higher reaction temperatures. © 2002 Elsevier Science Ltd. All rights reserved.

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