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A new and efficient catalytic isomerization of cis- and trans-epoxides
Journal article   Peer reviewed

A new and efficient catalytic isomerization of cis- and trans-epoxides

Ching-Yu Lo, Sitaram Pal, Arjan Odedra and Rai-Shung Liu
Tetrahedron Letters, Vol.44(15), pp.3143-3146
07/04/2003

Abstract

We report new ruthenium-catalyzed cis-trans isomerization of various functionalized epoxides. Enantiospecific isomerization of chiral epoxides is achieved without loss of enantiopurity, and epimerization occurs only at the epoxide carbon of the activating group. © 2003 Elsevier Science Ltd. All rights reserved.

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