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A novel palladium-catalyzed tandem dimerization and cyclization of acetylenic ketones. A convenient method for 3,3'-bifurans
Journal article   Peer reviewed

A novel palladium-catalyzed tandem dimerization and cyclization of acetylenic ketones. A convenient method for 3,3'-bifurans

Arumugasamy Jeevanandam, Kesavaram Narkunan, Charles Cartwright and Yong-Chien Ling
Tetrahedron Letters, Vol.40(26), pp.4841-4844
25/06/1999

Abstract

Alkynones undergo rearrangement in the presence of Pd(PPh 3 ) 4 and triethylamine in tetrahydrofuran at room temperature to give 2,5-substituted furans, but under similar conditions PdCl 2 (PPh 3 ) 2 , by a tandem dimerization and cyclization, gives 3,3'-bifurans predominantly.

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