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A selective and sensitive fluorescent albumin probe for the determination of urinary albumin
Journal article

A selective and sensitive fluorescent albumin probe for the determination of urinary albumin

Ying-Yi Wu, Wan-Ting Yu, Tai-Cheng Hou, Tao-Kai Liu, Chi-Ling Huang, I.-Chia Chen and Kui-Thong Tan
Chemical Communications, Vol.50(78), pp.11507-11510
09/10/2014

Abstract

In this communication, we report a simple albumin probe based on a fluorescent molecular rotor for the detection of trace albumin levels in urine. In the presence of albumin, the probe exhibits remarkable 400-fold fluorescence enhancement with high selectivity and sensitivity. The probe was successfully applied in the quantitative detection of urinary albumin.

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