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A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining
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A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining

Bor-Sen Chen, Shih-Kuang Yang, Chung-Yu Lan 和 Yung-Jen Chuang
BioMed Central BMC Medical Genomics, (1), 頁.46
2008
DOI: https://doi.org/10.1186/1755-8794-1-46

摘要

systems biology approach;gene regulatory network;systemic inflammation;microarray;databases mining;Data mining;dynamic network analyses;gene regulatory network;inflammatory response system;gene network perturbation method;systemic inflammation.
In this study, Data mining and dynamic network analyses were integrated to examine the gene regulatory network in the inflammatory response system. Compared with previous methodologies reported in the literatures, the proposed gene network perturbation method has shown a great improvement in analyzing the systemic inflammation.

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