Abstract
Acute kidney injury is commonly observed in hospitalized patients as well as cancer patients, and is associated with poor prognosis. Standard chemotherapy for lung cancer includes platinum-based agents, among which cisplatin is well known for inducing nephrotoxicity. Patients exhibiting risk factors for kidney injury warrant close monitoring while receiving cisplatin-based chemotherapy. Immune checkpoint inhibitors are another option for lung cancer treatment, and these agents may also lead to acute kidney injury, with acute interstitial nephritis being the most common pathological change. Previous study has shown that acute kidney injury in lung cancer patients receiving palliative chemotherapy does not appear to be associated with poorer prognosis, likely due to patient characteristics or drug dosage.