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An efficient method for the generation of N-methylnitrones
Journal article   Peer reviewed

An efficient method for the generation of N-methylnitrones

Jeffrey A. Robl and Jih Ru Hwu
Journal of Organic Chemistry, Vol.50(26), pp.5913-5916
1985

Abstract

N-Methylnitrones can be generated in good-to-excellent yields from aldehydes and ketones with a stoichiometric amount of N-methyl-N,O-bis(trimethylsilyl)hydroxylamine under very mild conditions and their formation, involving a bimolecular push-pull type mechanism, is discussed. © 1985 American Chemical Society.

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