摘要
The nanomechanical characteristics of the membrane cytoskeleton of human erythrocytes were studied using atomic force microscopy (AFM). The self-assembly, fine structure, cell diameter, thickness, and reticulate cytoskeleton of erythrocytes on the mica surface were investigated. The adhesive forces that correspond to the membrane elasticity of various parts of the erythrocyte membrane surface were measured directly by AFM to be 0.64±0.14 nN for cell indentation, 4.2±0.7 nN for cell hump, and 11.5 nN for side waist, respectively. The deformation of erythrocytes was discussed. Standing waves on the membrane that were set up by increased AFM amplitude were observed. The propagating velocity on the erythrocyte membrane was estimated to be ∼2.02× 10-2 ms. Liquid physiological conditions were considered throughout. © 2007 American Institute of Physics.