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C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy
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C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

Dong-Hua Wan, Bi-Yuan Zheng, Mei-Rong Ke, Ji-Ying Duan, Yun-Quan Zheng, Chih-Kuang YehJian-Dong Huang
Chemical Communications, 卷.53(29), 頁碼.4112-4115
2017

摘要

Catalysis Electronic Optical and Magnetic Materials Ceramics and Composites Chemistry (all) Surfaces Coatings and Films Metals and Alloys Materials Chemistry
C-Phycocyanin (CPC) as a tumour-associated macrophage (TAM)-targeted photosensitiser has been first proved, and used as a vehicle of zinc phthalocyanine (ZnPc) to fabricate a ZnPc-CPC conjugate, which exhibits an efficient in vitro photodynamic activity, and selectively accumulates in tumour sites probably due to the affinity to TAM.

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