CBr4-photoirradiation protocol for chemoselective deprotection of acid labile primary hydroxyl protecting groups

Ming-Yi Chen; Laxmikant N. Patkar; Mi-Dan Jan; Adam Shih-Yuan Lee; Chun-Cheng Lin

doi:10.1016/j.tetlet.2003.10.205

CBr4-photoirradiation protocol for chemoselective deprotection of acid labile primary hydroxyl protecting groups

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CBr4-photoirradiation protocol for chemoselective deprotection of acid labile primary hydroxyl protecting groups

Ming-Yi Chen, Laxmikant N. Patkar, Mi-Dan Jan, Adam Shih-Yuan Lee 和 Chun-Cheng Lin

Tetrahedron Letters, 卷.45(3), 頁碼.635-639

01/2004

DOI: https://doi.org/10.1016/j.tetlet.2003.10.205

摘要

Biochemistry

Drug Discovery

Organic Chemistry

CBr ₄ -photoirradiation protocol was found to be a mild, highly efficient and selective method for deprotection of isopropylidene, benzylidene, triphenylmethyl and tert-butyldimethylsilyl protecting groups on sugar molecules. The conditions of this reaction can also be used to cleave peptides off from acid-labile resin linkers in solid-phase peptide synthesis. © 2003 Elsevier Ltd. All rights reserved.

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題名: CBr4-photoirradiation protocol for chemoselective deprotection of acid labile primary hydroxyl protecting groups
創作者：: Ming-Yi Chen (作者) - Department of General Education , Taipei Nursing College
Laxmikant N. Patkar (作者) - Institute of Chemistry, Academia Sinica
Mi-Dan Jan (作者) - Institute of Chemistry, Academia Sinica
Adam Shih-Yuan Lee (作者) - Tamkang University
Chun-Cheng Lin (作者) - Institute of Chemistry, Academia Sinica
學術資源類型: 期刊文章
出版日期: 01/2004
出版資訊: Tetrahedron Letters, 卷.45(3), 頁碼.635-639
語言: 英語

CBr4-photoirradiation protocol for chemoselective deprotection of acid labile primary hydroxyl protecting groups

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