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CO2-Enhanced Production and Synthesis of 2,5- Furandicarboxylic Acid under CO2 Flow through Henkel Reaction
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CO2-Enhanced Production and Synthesis of 2,5- Furandicarboxylic Acid under CO2 Flow through Henkel Reaction

Po-Hsun Chang, David Shan-Hill Wong, John Di-Yi Ou, Yung-Tin PanShi-Shang Jang
European Journal of Organic Chemistry
2023

摘要

2,5-furandicarboxylic acid atmospheric pressure CO2 flow Henkel reaction zinc chloride Physical and Theoretical Chemistry Organic Chemistry
The present study investigated the preparation of 2,5-furandicarboxylic acid (FDCA) via the Henkel reaction between furoic acid alkali metal salts and zinc chloride under a continuous CO 2 flow at atmospheric pressure. The results obtained were compared with those of previous studies that used high-pressure conditions or toxic cadmium catalysts. The pathways and rate-determining steps of the reaction are revealed for the first time. Furthermore, the enhanced formation of FDCA through the promotion of carboxyl exchange and rearrangement during the reaction under a CO 2 flow was examined. The CO 2 -rich environment afforded a high FDCA yield of 86.30 %, which is the highest yield obtained to date using the Henkel reaction. The findings of this study offer economically improved conditions for large-scale FDCA production.

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https://doi.org/10.1002/ejoc.202300396檢視
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