Logo image
Cancer Therapy: Nucleus‐Targeting Gold Nanoclusters for Simultaneous In Vivo Fluorescence Imaging, Gene Delivery, and NIR‐Light Activated Photodynamic Therapy (Adv. Funct. Mater. 37/2015)
期刊文章   同儕審查

Cancer Therapy: Nucleus‐Targeting Gold Nanoclusters for Simultaneous In Vivo Fluorescence Imaging, Gene Delivery, and NIR‐Light Activated Photodynamic Therapy (Adv. Funct. Mater. 37/2015)

Raviraj Vankayala, Chien‐Lin Kuo, Karthik Nuthalapati, Chi‐Shiun Chiang 和 Kuo Chu Hwang
Advanced functional materials, 卷.25(37), 頁碼.5933-5933
01/10/2015

摘要

DNA damage fluorescence imaging gene delivery gold nanoclusters nucleus targeting photodynamic therapy singlet oxygen
Nucleus‐targeting gold nanoclusters (TAT peptide‐Au NCs) can act as intrinsic fluorescence probe for bioimaging, as shown by K. C. Hwang and co‐workers on page 5934. The nanoclusters also sensitize formation of singlet oxygen upon NIR light activation, to exert effective photodynamic therapeutic effects in killing cancer cells via subsequent DNA damage inside the nucleus, without using any additional photosensitizers.

檔案與連結 (1)

url
https://doi.org/10.1002/adfm.201570247檢視
已出版(紀錄版本) 開放

相關連結

指標

1 檢視次數

詳細資料

Logo image