摘要
Carbohydrate-lectin recognition plays important roles in cell-cell communication, proliferation, and differentiation. We report here a new approach of using a carbohydrate-encapsulated gold nanoparticle (shown in purple) as an affinity probe for the efficient separation and enrichment of target proteins, and then protein identification and epitope mapping by MALDI-TOF MS. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.