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Cell kinetics and radiosensitivity of cervical squamous cell carcinoma
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Cell kinetics and radiosensitivity of cervical squamous cell carcinoma

Chi-An Chen, Chih-Cheng Wu, Tzer-Ming Chen, Louis T. Lui, Chin-Feng ChangChang-Yao Hsieh
Cancer Letters, 卷.82(2), 頁碼.135-140
07/1994
PMID: 8050083

摘要

Cell kinetics Cervical carcinoma Flow cytometry Radiosensitivity Oncology Cancer Research
Flow cytometry analyses of tumors from 12 patients with cervical squamous cell carcinoma under radiotherapy were performed in this preliminary study. Six patients with a high (>10%) G2/M fraction before treatment showed greater than 50% tumor reduction after initial 2000 cGy radiotherapy. Only two out of six patients with a low (<10%) G2/M fraction before treatment responded favorably and three of them already had recurrence during the follow-up period of 33-40 months. Hyperploidy (DNA index > 1.1) was observed in 5 patients; all of them responded well to radiotherapy in contrast to three out of seven diploid tumors. © 1994.

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