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Circadian lighting effect for inpatients with schizophrenia: A prospective cohort study
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Circadian lighting effect for inpatients with schizophrenia: A prospective cohort study

Ya-Chi Tsai, Jwo-Huei Jou, Ching-Chi Hsu, Ming-Chang Shih, Luke The 和 Dipanshu Sharma
Brain and behavior, 卷.14(8)
01/08/2024
PMID: 39183509
Web of Science ID: WOS:001297959000001

摘要

Adult Brief Psychiatric Rating Scale Circadian Rhythm - physiology Female Humans Inpatients Lighting Male Mental Status and Dementia Tests Middle Aged Prospective Studies Schizophrenia - physiopathology Schizophrenia - therapy Schizophrenic Psychology
In schizophrenia, nonspecific lighting likely causes sleep timing disturbances, leading to distress and poorer clinical status. However, the effect of exposure to circadian lighting on psychopathology outcome in schizophrenia remains unknown. Hence, this study aimed to develop such an intervention and investigate its impact on schizophrenia. Twenty schizophrenia patients at a psychiatric nursing institute were monitored over 10 weeks, with assessments using the Brief Psychiatric Rating Scale (BPRS) and Mini-Mental State Examination (MMSE) conducted at baseline, weeks 3 (T1), 7 (T2), and 10 (T3). Circadian lighting significantly improved BPRS scores between T1-T2 (p < .05) and T1-T3 (p < .001), with affectivity scores also showing significant enhancements postintervention. Notably, female participants exhibited substantial improvements in BPRS scores from T1 to T3 (p < .01), while male participants demonstrated significant gains in MMSE scores from T1 to T2 (p < .01). Circadian lighting presents a promising intervention for improving psychiatric outcomes in schizophrenia, with distinct benefits observed across different psychopathological aspects and genders. These findings underscore the potential of lighting chronotherapy in psychiatric clinical practice and warrant further exploration in related research.

檔案與連結 (1)

url
https://doi.org/10.1002/brb3.70003檢視
已出版(紀錄版本)

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InCites亮點

本研究成果之相關指標(擷取自 InCites Benchmarking & Analytics)

引用書目主題
1 Clinical & Life Sciences
1.137 Sleep Science & Circadian Systems
1.137.217 Circadian-Melatonin
Web Of Science研究領域
Behavioral Sciences
Neurosciences
ESI研究領域
Neuroscience & Behavior

聯合國永續發展目標(SDGs)

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#3 Good Health and Well-Being

來源:來自InCites的SDGs

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