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Circulating 25-hydroxyVitamin D and physical performance in older adults: A nationwide study in Taiwan
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Circulating 25-hydroxyVitamin D and physical performance in older adults: A nationwide study in Taiwan

Shu-Chun Chuang, Hui-Ling Chen, Wei-Ting Tseng, I-Chien Wu, Chih-Cheng Hsu, Hsing-Yi Chang, Yii-Der Ida Chen, Marion M Lee, Kiang LiuChao Agnes Hsiung
American Journal of Clinical Nutrition, 卷.104(5), 頁碼.1334-1344
11/2016
PMID: 27733394

摘要

Epidemiology HALST Lifestyle factors Physical performance Vitamin D Medicine (miscellaneous) Nutrition and Dietetics
Background: A previous study indicated that 31% of the elderly in Taiwan have a Vitamin D deficiency. Vitamin D adequacy has been associated with physical performance in the elderly. Objectives: The first aim of the current study was to identify the determinants for Vitamin D deficiency. The second aim was to evaluate the association between Vitamin D status and physical performance. Design: A total of 5664 community-dwelling participants aged 55 y were recruited since 2008. Plasma total 25-hydroxyVitamin D concentrations were originally determined by ELISA and calibrated to a chemiluminescence measurement. Physical performance was assessed by handgrip strength, the Short Physical Performance Battery, timed up and go, a 6-min walk test, and single-leg stands. Multiple linear regression and logistic regression were used to estimate the cross-sectional associations. Results: Vitamin D inadequacy (,50 nmol/L) was related to higher education (P-trend , 0.01), body mass index [(BMI; in kg/m2) ORs (95% CIs) for 30 compared with 18.5 to ,25 were 1.78 (1.14, 2.78) for men and 1.53 (1.11, 2.11) for women], and vegetable intake [fourth compared with first quartile, 1.58 (1.15, 2.18) for men and 2.38 (1.82, 3.12) for women]. Higher intakes of fish [fourth compared with first quartile, 0.44 (0.33, 0.59) for men and 0.27 (0.21, 0.36) for women] and milk [fourth compared with first quartile, 0.46 (0.31, 0.69) for men and 0.69 (0.49, 0.95) for women] were associated with lower risk of Vitamin D inadequacy. Few subjects had 25-hydroxyVitamin D concentrations ,30 nmol/L. Above that concentration, there was no doseeffect relation with physical performance except for single-leg stands. Conclusions: The factors associated with Vitamin D inadequacy in Taiwan were higher education, higher BMI, and lower fish and milk intakes. No dose-effect relation existed between Vitamin D concentration and physical performance except for single-leg stands.

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