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Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells
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Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

Shih-Feng Tsai, David I. K. Martin, Leonard I. Zon, Alan D. D'Andrea, Gordon G. WongStuart H. Orkin
Nature, 卷.339(6224), 頁碼.446-451
1989
PMID: 2725678

摘要

Multidisciplinary
Genes expressed in erythroid cells contain binding sites for a cell-specific factor believed to be an important regulator for this haematopoietic lineage. Using high-level transient expression in mammalian cells, we have identified complementary DNA encoding the murine protein. The factor, a new member of the zinc-finger family of DNA-binding proteins, is restricted to erythroid cells at the level of RNA expression and is closely homologous between mouse and man. © 1989 Nature Publishing Group.

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