Core-shell nanocapsules stabilized by single-component polymer and nanoparticles for magneto-chemotherapy/hyperthermia with multiple drugs

Shang-Hsiu Hu; Bang-Jie Liao; Chin-Sheng Chiang; Po-Jung Chen; I-Wei Chen; San-Yuan Chen

doi:10.1002/adma.201201251

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Core-shell nanocapsules stabilized by single-component polymer and nanoparticles for magneto-chemotherapy/hyperthermia with multiple drugs

Journal article

Peer reviewed

Core-shell nanocapsules stabilized by single-component polymer and nanoparticles for magneto-chemotherapy/hyperthermia with multiple drugs

Shang-Hsiu Hu, Bang-Jie Liao, Chin-Sheng Chiang, Po-Jung Chen, I-Wei Chen and San-Yuan Chen

Advanced Materials, Vol.24(27), pp.3627-3632

17/07/2012

DOI: https://doi.org/10.1002/adma.201201251

Abstract

double emulsions

hyperthermia

iron oxide nanoparticles

nanocapsules

synergic therapy

Iron-oxide-containing double emulsion capsules carrying both hydrophilic and hydrophobic therapeutic molecules can deliver drugs and energy on demand in vivo. Magneto-chemotherapy/hyperthermia involves a burst-like release of hydrophilic doxorubicin and hydrophobic paclitaxel, remotely triggered by a high frequency magnetic field, which also releases energy via internalized iron oxide nanoparticles, all contributing to cell kill. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Title: Core-shell nanocapsules stabilized by single-component polymer and nanoparticles for magneto-chemotherapy/hyperthermia with multiple drugs
Creators - without role: Shang-Hsiu Hu - Department of Materials Science and Engineering , National Chiao Tung University
Bang-Jie Liao - Department of Materials Science and Engineering , National Chiao Tung University
Chin-Sheng Chiang - Department of Materials Science and Engineering , National Chiao Tung University
Po-Jung Chen - Department of Materials Science and Engineering , National Chiao Tung University
I-Wei Chen - University of Pennsylvania
San-Yuan Chen - Department of Materials Science and Engineering , National Chiao Tung University
Identifiers: 9957777503706774
Academic Unit: Institute of Analytical and Environmental Sciences, College of Nuclear Science, National Tsing Hua University
Language: English
Resource Type: Journal article
Publication Details: Advanced Materials, Vol.24(27), pp.3627-3632

Core-shell nanocapsules stabilized by single-component polymer and nanoparticles for magneto-chemotherapy/hyperthermia with multiple drugs

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