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Cover Feature: Automatic Full Glycan Structural Determination through Logically Derived Sequence Tandem Mass Spectrometry (ChemBioChem 18/2019)
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Cover Feature: Automatic Full Glycan Structural Determination through Logically Derived Sequence Tandem Mass Spectrometry (ChemBioChem 18/2019)

Shang‐Ting Tsai, Chia Yen Liew, Chen Hsu, Shih‐Pei Huang, Wei‐Chien Weng, Yu‐Hsiang Kuo 和 Chi‐Kung Ni
Chembiochem : a European journal of chemical biology, 卷.20(18), 頁碼.2272-2272
16/09/2019

摘要

glycoconjugates HPLC mass spectrometry oligosaccharides structure elucidation
The structures of oligosaccharides, including the differentiation of the diastereomer and anomer of each monosaccharide and the identification of linkage positions of each glycosidic bond, can be determined by a new method: tandem mass spectrometry guided by a logically derived sequence (LODES). The entire procedure of mass spectrum measurement guided by LODES can be programmed in a computer for automatic structural identification of the oligosaccharides eluted from high‐performance liquid chromatography. More information can be found in the full paper by C.‐K. Ni et al. on page 2351 in Issue 18, 2019 (DOI: 10.1002/cbic.201900228).

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