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Current diagnostic tools for coronaviruses–From laboratory diagnosis to POC diagnosis for COVID-19
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Current diagnostic tools for coronaviruses–From laboratory diagnosis to POC diagnosis for COVID-19

Yung-Chih Wang, Yi-Tzu Lee, Ting Yang, Jun-Ren Sun, Ching-Fen ShenChao-Min Cheng
Bioengineering and Translational Medicine
2020

摘要

coronaviruses COVID-19 diagnostics point-of-care Biomedical Engineering Biotechnology Medicine (all) Pharmaceutical Science
The Coronavirus-2019 (COVID-19) pandemic has put tremendous strain on healthcare systems worldwide. It is challenging for clinicians to differentiate COVID-19 from other acute respiratory tract infections via clinical symptoms because those who are infected display a wide range of symptoms. An effective, point-of-care (POC) diagnostic tool could mitigate healthcare system strain, protect healthcare professionals, and support quarantine efforts. We believe that a POC tool can be developed that would be rapid, easy to use, and inexpensive. It could be used in the home, in resource-limited areas, and even in clinical settings. In this article, we summarize the current state of POC tools and propose an all-in-one, highly sensitive POC assay that integrates antibody detection, protein detection, and serum cytokine detection to diagnose COVID-19 infection. We believe this article will provide insight into the current state of POC diagnostics for COVID-19, and promote additional research and tool development that could be exceptionally impactful.

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https://doi.org/10.1002/btm2.10177檢視
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