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Determination of Δ9-tetrahydrocannabinol in indoor air as an indicator of marijuana cigarette smoking using adsorbent sampling and in-injector thermal desorption gas chromatography-mass spectrometry
Journal article   Peer reviewed

Determination of Δ9-tetrahydrocannabinol in indoor air as an indicator of marijuana cigarette smoking using adsorbent sampling and in-injector thermal desorption gas chromatography-mass spectrometry

Su-Lien Chou, Yong-Chien Ling, Mo-Hsiung Yang and Chung-Yen Pai
Analytica Chimica Acta, Vol.598(1), pp.103-109
15/08/2007

Abstract

9-Tetrahydrocannabinol Gas chromatography-mass spectrometry Indoor air Marijuana cigarette smoking
The marijuana leaves are usually mixed with tobaccos and smoked at amusement places in Taiwan. Recently, for investigation-legal purposes, the police asked if we can identify the marijuana smoke in a KTV stateroom (a private room at the entertainment spot for singing, smoking, alcohol drinking, etc.) without marijuana residues. A personal air-sampler pump fitted with the GC liner-tube packed with Tenax-TA adsorbent was used for air sampling. The GC-adsorbent tube was placed in the GC injector port and desorbed directly, followed by GC-MS analysis for the determination of Δ 9 -tetrahydrocannabinol (Δ 9 -THC) in indoor air. The average desorption efficiency and limit of detection for Δ 9 -THC were 89% and 0.1 μg m -3 , respectively, approximately needing 1.09 mg of marijuana leaves smoked in an unventilated closed room (3.0 m × 2.4 m × 2.7 m) to reach this level. The mean Δ 9 -THC contained in the 15 marijuana plants seized from diverse locations was measured to be 0.32%. The Δ 9 -THC in room air can be successfully identified from mock marijuana cigarettes, mixtures of marijuana and tobacco, and an actual case. The characteristic Δ 9 -THC peak in chromatogram can serve as the indicator of marijuana. Positive result suggests marijuana smoking at the specific scene in the recent past, facilitating the formulation of further investigation. © 2007 Elsevier B.V. All rights reserved.

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