Logo image
Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents
Journal article

Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

Jih Ru Hwu, Chii Shyang Yau, Fu Yuan Tsai and Shwu-Chen Tsay
Journal of the Chemical Society - Perkin Transactions 1, (17), pp.2451-2453
07/09/1997

Abstract

Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO and singlet oxygen, respectively.

Metrics

1 Record Views

Details

Logo image