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Distinguishing cells by their first-order transient motion response under an optically induced dielectrophoretic force field
Journal article   Open access   Peer reviewed

Distinguishing cells by their first-order transient motion response under an optically induced dielectrophoretic force field

Yuliang Zhao, Wenfeng Liang, Guanglie Zhang, John D. Mai, Lianqing Liu, Gwo-Bin Lee and Wen J. Li
Applied Physics Letters, Vol.103(18), 183702
28/10/2013

Abstract

This letter reports our characterization of the transient motion of cells under an optically induced dielectrophoresis (ODEP) force field. Different types of human cells repeatably undergo a first-order transient motion response when subjected to a specific ODEP force field. A kernel function is derived to describe this transient motion. This function can be generally matched to experimental data for Raji cells and red blood cells by measuring two parameters: the initial velocity and the transient time-constant. They are uniquely different for Raji cells and RBCs. Support vector machine is used to distinguish between them based on their transient response characteristics. © 2013 AIP Publishing LLC.
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https://doi.org/10.1063/1.4827300View
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