Diverse cyclization catalyzed by in(OTf)3 for the convergent assembly of substituted tetrahydrofurans and tetrahydropyrans

Teck-Peng Loh; Qi-Ying Hu; Kui-Thong Tan; Hin-Soon Cheng

doi:10.1021/ol016228o

Back

Diverse cyclization catalyzed by in(OTf)3 for the convergent assembly of substituted tetrahydrofurans and tetrahydropyrans

Journal article

Peer reviewed

Diverse cyclization catalyzed by in(OTf)3 for the convergent assembly of substituted tetrahydrofurans and tetrahydropyrans

Teck-Peng Loh, Qi-Ying Hu, Kui-Thong Tan and Hin-Soon Cheng

Organic Letters, Vol.3(17), pp.2669-2672

23/08/2001

DOI: https://doi.org/10.1021/ol016228o

Abstract

(Equation presented) A novel In(OTf) ₃ -catalyzed (3,5) oxonium-ene type cyclization for the facile construction of various multisubstituted tetrahydrofurans and tetrahydropyrans was successfully developed. Further mechanistic investigations unveiled an In(OTf) ₃ -catalyzed skeletal reorganization of the tetrahydrofuran to its thermodynamic isomer under thermal conditions.

Metrics

1 Record Views

See more details

Details

Title: Diverse cyclization catalyzed by in(OTf)3 for the convergent assembly of substituted tetrahydrofurans and tetrahydropyrans
Creators - without role: Teck-Peng Loh - Department of Chemistry , National University of Singapore
Qi-Ying Hu - Department of Chemistry , National University of Singapore
Kui-Thong Tan - Department of Chemistry , National University of Singapore
Hin-Soon Cheng - Department of Chemistry , National University of Singapore
Publication Details: Organic Letters, Vol.3(17), pp.2669-2672
Identifiers: 9957775449606774
Academic Unit: Institute of Analytical and Environmental Sciences, College of Nuclear Science, National Tsing Hua University
Language: English
Resource Type: Journal article

Diverse cyclization catalyzed by in(OTf)3 for the convergent assembly of substituted tetrahydrofurans and tetrahydropyrans

Abstract

Related links

Metrics

Details

National Tsing Hua University Social media