Abstract
(Chemical Presented) A highly stereoselective AuCl 3 -catalyzed hydrative cyclization of 1-epoxy-1-alkynylcyclopropanes was observed for cis-epoxides. Since this cyclization produced 1-oxyallyl cations efficiently, we accomplished a two-step [4+2] annulation of epoxyalkynes with dienes and enones, to provide complex oxacyclic compounds with excellent diastereoselectivity (see scheme). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.