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EPR, UV - vis, IR, and X-ray demonstration of the anionic dimeric dinitrosyl iron complex [(NO)2Fe(μ-StBu) 2Fe(NO)2]-: Relevance to the products of nitrosylation of cytosolic and mitochondrial aconitases, and high-potential iron proteins
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EPR, UV - vis, IR, and X-ray demonstration of the anionic dimeric dinitrosyl iron complex [(NO)2Fe(μ-StBu) 2Fe(NO)2]-: Relevance to the products of nitrosylation of cytosolic and mitochondrial aconitases, and high-potential iron proteins

Chih-Chin Tsou, Tsai-Te LuWen-Feng Liaw
Journal of the American Chemical Society, 卷.129(42), 頁碼.12626-12627
10/2007
PMID: 17900121

摘要

Chemistry (all)
Complexes [(NO) 2 Fe(S- t Bu) 2 ] - (3-Na) and [Fe 2 (μ-S t Bu) 2 (NO) 4 ] (1) are in dynamic equilibrium in the protic solvent MeOH. The subsequent addition of the equivalent of cobaltocene into the MeOH solution mixture of complexes 3-Na and 1 led to the formation of the fully delocalized mixed-valence [Fe(μ-S- t Bu)(NO) 2 ] 2 - (2) characterized by IR, UV-vis, EPR, SQUID, and single-crystal X-ray diffraction. The EPR spectrum of complex 2 displaying an axial signal at g ⊥ = 2.009, g∥ = 1.965 (77 K) and an isotropic signal at g = 1.998 (298 K), identical to the EPR spectra of reduction of dinitrosyl iron complex (DNIC)/aconitase obtained from nitrosylation of aconitase and reduction of HiPIP-containing protein-bound DNIC, suggests that the [4Fe-4S] 2+ clusters of aconitase/HiPIP were nitrosylated to produce a mixture of the monomeric and dimeric DNICs. Copyright © 2007 American Chemical Society.

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