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Early detection of bone marrow involvement in extramedullary plasmacytoma by whole-body F-18 FDG positron emission tomography
期刊文章   同儕審查

Early detection of bone marrow involvement in extramedullary plasmacytoma by whole-body F-18 FDG positron emission tomography

Takashi Kato, Eriko Tsukamoto, Takeshi Nishioka, Akira Yamazaki, Hiroshi Shirato, Sumiko Kobayashi, Masahiro Asaka, Masahiro Imamura, Nagara Tamaki 和 Fang-Hsin Chen
Clinical nuclear medicine, 卷.25(11), 頁碼.870-873
11/2000
PMID: 11079582
Web of Science ID: WOS:000165048600003

摘要

Biological and medical sciences Blood cells Hematologic and hematopoietic diseases Investigative techniques, diagnostic techniques (general aspects) Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Radionuclide investigations

The utility of positron emission tomography (PET) with the glucose analog 2-deoxy-2-[F-18] fluoro-D-glucose (F-18 FDG) in plasmacytoma has not been well evaluated. The authors report a case of extramedullary plasmacytoma (EMP) in which whole-body F-18 FDG PET was useful in the early detection of bone marrow involvement. A 34-year-old woman had EMP without histologic or radiologic evidence of bone lesions. However, the early phase of bone marrow involvement was considered because of spotty accumulation shown by F-18 FDG PET. A follow-up F-18 FDG PET study after radiotherapy showed intense multifocal accumulation in the bone marrow, which was confirmed on bone marrow aspiration as abnormal proliferation of plasma cells. Whole-body F-18 FDG PET has the potential to detect the early phase of bone marrow involvement in patients with EMP.

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