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Expeditious routes to multiply functionalized pyrans
Journal article   Peer reviewed

Expeditious routes to multiply functionalized pyrans

Samuel Danishefsky, Daniel F. Harvey, George Quallich and Biing Jiun Uang
Journal of Organic Chemistry, Vol.49(2), pp.392-393
1984

Abstract

The scope of the Lewis acid catalyzed cyclocondensation reaction of activated dienes and aldehydes has been investigated. With a 3-(trialkylsilyl)oxy group in the basic diene, the reaction has been shown to be feasible with 1,1-dimethoxy, 1-(silyloxy)-1-alkyl, and 1-alkyl substituents. Rapid and general routes to various derivatives of 4-pyranone are thus available. © 1984 American Chemical Society.

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