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Fast detection of a protozoan pathogen, Perkinsus marinus, using AlGaN/GaN high electron mobility transistors
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Fast detection of a protozoan pathogen, Perkinsus marinus, using AlGaN/GaN high electron mobility transistors

Yu-Lin Wang, B.H. Chu, K.H. Chen, C.Y. Chang, T.P. Lele, G. Papadi, J.K. Coleman, B.J. Sheppard, C.F. Dungen, S.J. Pearton, …
Applied Physics Letters, 卷.94(24), 243901
2009

摘要

Physics and Astronomy (miscellaneous)
Antibody-functionalized, Au-gated AlGaN/GaN high electron mobility transistors (HEMTs) were used to detect Perkinsus marinus. The antibody was anchored to the gate area through immobilized thioglycolic acid. The AlGaN/GaN HEMT drain-source current showed a rapid response of less than 5 s when the infected solution was added to the antibody-immobilized surface. The sensor can be recycled with a phosphate buffered saline wash. These results clearly demonstrate the promise of field-deployable electronic biological sensors based on AlGaN/GaN HEMTs for Perkinsus marinus detection. © 2009 American Institute of Physics.

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