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Formation of seven-membered-ring fused bithiophene derivatives by nosyl annulation
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Formation of seven-membered-ring fused bithiophene derivatives by nosyl annulation

Atsunori Mori, Masayasu Hayashi, Mitsuru Matsuoka, Shiomi Ashida, Yukiko Ito, Kohei Hosokawa, Toyoko Suzuki, Kentaro Okano, Chi-Hsien WangMasaki Horie
Heterocycles, 卷.101(2), 頁碼.461-470
2020

摘要

Analytical Chemistry Pharmacology Organic Chemistry
Nosyl annulation of a bithiophene derivative with nosylamide (NsNH2) gives a 5-7-5 fused N, S-heterocyclic compound. The detailed molecular structure of the obtained nosylamide was analyzed by single-crystal X-ray crystallography. The obtained product was transformed into several amines and amides. The C-Br bond at the fused heterocycle was also subjected to cross-coupling reactions, where the nosyl group was found to be tolerant.

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https://doi.org/10.3987/COM-19-S(F)29檢視
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