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Functionizalized Graphene Nanocomposites for Enhancing Photothermal Therapy
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Functionizalized Graphene Nanocomposites for Enhancing Photothermal Therapy

Yu-Wei Chen, Yu-Lin Su, Shang-Hsiu HuSan-Yuan Chen
Advanced Drug Delivery Reviews Advanced Drug Delivery Reviews, 卷.105(B), 頁碼.190-204
2016

摘要

Graphene;Photothermal therapy;Composites;Drug delivery;Tumor therapy
Graphene and its derivatives have unique physical and chemical properties that make them promising vehicles for photothermal therapy (PTT)-based cancer treatment. With intrinsic near-infrared (NIR) absorption properties, graphene-based nanomaterials can be used for PTT and other therapeutics, particularly in combination therapy, to provide successful thermal ablation of cancer cells. In the recent years, advances in graphene-based PTT have produced efficient and efficacious tumor inhibition via nanomaterial structural design and different functionalizations of graphene-derived nanocomposites. Graphene-based nanosystems exhibit multifunctional properties that are useful for PTT applications including enhancement of multimodalities, guided imaging, enhanced chemotherapy and low-power efficient PTT for optimum therapeutic efficiency. Therefore, in this review, we address critical issues and future aspects of PTT-based combination therapy.

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