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Generation and aldol reaction of enolate anion adjacent to a η3-alln-mo(co)2 Cp moiety. Anew approach to the to the stereoselective synthesis of 1,3,5-triol and 2-vinyl-3-hydroxyl-tetrahydrofuran.
Journal article   Peer reviewed

Generation and aldol reaction of enolate anion adjacent to a η3-alln-mo(co)2 Cp moiety. Anew approach to the to the stereoselective synthesis of 1,3,5-triol and 2-vinyl-3-hydroxyl-tetrahydrofuran.

Shie-Hsiung Lin, Wen-Jung Vong, Cnih-Yi Cheng, Sue-Lein Wang and Rai-Shung Liu
Tetrahedron Letters, Vol.31(52), pp.7645-7648
1990
DOI: https://doi.org/10.1016/S0040-4039(00)97321-0

Abstract

The enolate of CpMo(CO) 2 (syn-η 3 -1-C 3 H 4 COCH 3 ) generated with lithium diisopropylamide in THF undergoes diastereoselective aldol reaction with benzaldehyde; the alcohol thus formed has been utilized for stereoselective synthesis of 1.5-diphenyl-2-vinyl-pentan-1,3,5-triol and 2-vinyl-3-hydroxyl-5-phenyl-tetrahydrofuran. © 1990.

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