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Gold-catalyzed cyclization-cycloaddition cascade reactions of allenyl acetals with nitrones
Journal article   Peer reviewed

Gold-catalyzed cyclization-cycloaddition cascade reactions of allenyl acetals with nitrones

Dhananjayan Vasu and Rai-Shung Liu
Chemistry - A European Journal, Vol.18(43), pp.13638-13641
22/10/2012

Abstract

[3+2]-cycloaddition allenes gold homogeneous catalysis nitrones
Gold and silver: When allenyl acetals and nitrones are treated with a catalytic amount of a gold complex and a silver salt they react through a cyclization-cycloaddition cascade reaction to give a mixture of diastereomeric tricyclic products. The mixture converges to a single product upon acid hydrolysis (see scheme). The key intermediate is postulated to be a 1-methoxyfulvene species. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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