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Gold-catalyzed intermolecular [4+2] and [2+2+2] cycloadditions of ynamides with alkenes
Journal article   Peer reviewed

Gold-catalyzed intermolecular [4+2] and [2+2+2] cycloadditions of ynamides with alkenes

Ramesh B. Dateer, Balagopal S. Shaibu and Rai-Shung Liu
Angewandte Chemie - International Edition, Vol.51(1), pp.113-117
02/01/2012

Abstract

cycloaddition enynes gold ynamides
As good as gold: Gold-catalyzed intermolecular [4+2] cycloadditions of 2-arylynamides with alkenes and gold-catalyzed [2+2+2] cycloadditions of terminal ynamides with enol ethers have been developed (see scheme). The [4+2] cycloaddition is compatible with a range of alkenes and arylynamides and the [2+2+2] cycloaddition can also accommodate a variety of different arylynamide and enol ether substrates. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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