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Gold-catalyzed reactions between alkenyldiazo carbonyl species and acetals
Journal article   Peer reviewed

Gold-catalyzed reactions between alkenyldiazo carbonyl species and acetals

Vinayak Vishnu Pagar, Appaso M. Jadhav and Rai-Shung Liu
Journal of Organic Chemistry, Vol.78(11), pp.5711-5716
2013

Abstract

In the presence of catalyst IPrAuSbF 6 catalyst (IPr = 1,3-bis(diisopropylphenyl)imidazol-2-ylidene), alkenyldiazo carbonyl species react with organic acetals to give E-configured alkyl 3,5-dimethoxy-5-pent-2- enoates stereoselectively. This reaction sequence comprises an initial Prins-type reaction, followed by gold carbene formation. © 2013 American Chemical Society.

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