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Intramolecular free radical cyclisation of α-anilino alkenenitriles
Journal article

Intramolecular free radical cyclisation of α-anilino alkenenitriles

Jim-Min Fang, Han-Ting Chang and Chun-Cheng Lin
Journal of the Chemical Society, Chemical Communications, (20), pp.1385-1386
1988

Abstract

Molecular Medicine
Upon treatment with tributylstannane, 2-anilino 2-alkenenitriles having halo substituents at appropriate positions undergo radical cyclisations to give cycloalkyl α-aminonitriles in a stereoselective manner.

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