Label-free, coupler-free, scalable and intracellular bio-imaging by multimode plasmonic resonances in split-ring resonators

Yueh-Chun Lai; Hsin-Cheng Lee; Shu-Wen Kuo; Cheng-Kuang Chen; Hsieh-Ting Wu; Oscar K. Lee; Ta-Jen Yen

doi:10.1002/adma.201200291

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Label-free, coupler-free, scalable and intracellular bio-imaging by multimode plasmonic resonances in split-ring resonators

Journal article

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Label-free, coupler-free, scalable and intracellular bio-imaging by multimode plasmonic resonances in split-ring resonators

Yueh-Chun Lai, Hsin-Cheng Lee, Shu-Wen Kuo, Cheng-Kuang Chen, Hsieh-Ting Wu, Oscar K. Lee and Ta-Jen Yen

Advanced Materials, Vol.24(23)

19/06/2012

DOI: https://doi.org/10.1002/adma.201200291

Abstract

bioimaging

biosensors

metamaterials

plasmonics

split-ring resonators

Intracellular imaging by exciting multimode resonances in spilt-ring resonators (SRRs) is presented. With advantages such as being label-free, coupler-free, having a tunable spectrum range and intracellular detection length, SRR microscopy is a strong competitor for surface plasmon resonance microscopy for observing cells. Its capability for constructing refractive index distribution images of cells is demonstrated. SRR microscopy offers a much simpler optical configuration and better penetration depth for truly whole-cell imaging applications. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Title: Label-free, coupler-free, scalable and intracellular bio-imaging by multimode plasmonic resonances in split-ring resonators
Creators - without role: Yueh-Chun Lai - Department of Materials Science and Engineering , National Tsing Hua University
Hsin-Cheng Lee - Department of Materials Science and Engineering , National Tsing Hua University
Shu-Wen Kuo - National Yang Ming University
Cheng-Kuang Chen - Department of Materials Science and Engineering , National Tsing Hua University
Hsieh-Ting Wu - Department of Materials Science and Engineering , National Tsing Hua University
Oscar K. Lee - National Yang Ming University Hospital
Ta-Jen Yen - Department of Materials Science and Engineering , National Tsing Hua University
Publication Details: Advanced Materials, Vol.24(23)
Identifiers: 9957769920106774
Academic Unit: Department of Materials Science and Engineering, College of Engineering, National Tsing Hua University
Language: English
Resource Type: Journal article

Label-free, coupler-free, scalable and intracellular bio-imaging by multimode plasmonic resonances in split-ring resonators

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