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Mobilization of qnrB2 and ISCR1 in plasmids
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Mobilization of qnrB2 and ISCR1 in plasmids

Ying-Tsong Chen, Tsai-Lien Liao, Yen-Ming Liu, Tsai-Ling Lauderdale, Jing-Jou YanShin-Feng Tsai
Antimicrobial Agents and Chemotherapy, 卷.53(3), 頁碼.1235-1237
03/2009
PMID: 19075060

摘要

Pharmacology (medical) Pharmacology Infectious Diseases
The DNA sequences of two IncHI2 plasmids, pEC-IMP and pEC-IMPQ, from metallo-β-lactamase- producing Enterobacter cloacae clinical isolates were determined. The two conjugative plasmids are almost identical, but pEC-IMPQ carries an additional segment containing an orf513 (1SCR1), a truncated 3' conserved sequence, and a qnrB2. Comparative analyses provide support for the proposed ISCR1-mediated gene mobilization. Copyright © 2009, American Society for Microbiology. All Rights Reserved.

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