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Molecular-level dengue fever diagnostics: Developing a combination of RT-LAMP and paper-based devices
期刊文章

Molecular-level dengue fever diagnostics: Developing a combination of RT-LAMP and paper-based devices

Shih-Jie Lo, Shih-Chun Yang, Da-Jeng Yao, Jiann-Hwa ChenChao-Min Cheng
IEEE Nanotechnology Magazine, 卷.6(4), 頁碼.26-30
2012

摘要

This article describes the development of an inexpensive but robust and easy-to-use point-of-care diagnostic device that can be used for the detection of dengue fever at the molecular level (i.e., the detection of dengue virus using a piece of paper). To date, the clinical diagnosis of dengue fever mainly relies on enzyme-linked immunosorbent assay-based examinations for a specific antigen. However, protein-based diagnostics are used at a relatively late stage of the infection, and there is a need to develop a simple and low-cost diagnostic device for the detection of dengue fever at the early stages of the infection. © 2007-2011 IEEE.

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