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N-arylalkyl-N-phenylhydroxylamines as novel photo-induced DNA-cleaving agents
Journal article

N-arylalkyl-N-phenylhydroxylamines as novel photo-induced DNA-cleaving agents

Jih Ru Hwu, Shwu-Chen Tsay, Buh-Luen Chen, Himatkumar V. Patel and Ching-Tai Chou
Journal of the Chemical Society, Chemical Communications, (12), pp.1427-1428
1994

Abstract

Single-strand cleavage of DNA was accomplished by photolysis of various N-arylalkyl-N-phenylhydroxylamines under aerobic conditions for 3 h with 312 nm UV light, which functioned as the trigger to initiate the new and controllable DNA cleavage process.

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