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Nickel-catalyzed cocyclotrimerization of arynes with diynes; a novel method for synthesis of naphthalene derivatives
Journal article   Open access   Peer reviewed

Nickel-catalyzed cocyclotrimerization of arynes with diynes; a novel method for synthesis of naphthalene derivatives

Jen-Chieh Hsieh and Chien-Hong Cheng
Chemical Communications, (19), pp.2459-2461
21/05/2005

Abstract

The NiBr 2 (dppe)-Zn system effectively catalyzes the [2 + 2 + 2] cocyclotrimerization of arynes with diynes, leading to substituted naphthalene derivatives in moderate to good yields. This cocyclotrimerization reaction shows excellent tolerance of functional groups and leads to products of 5- to 7-membered fused-ring sizes. © The Royal Society of Chemistry 2005.
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